Research Associate in Single molecule imaging of protein aggregates (Fixed Term) University of Cambridge, Department of Chemistry United Kingdom

Research Associate - Single molecule imaging of protein aggregates (Fixed Term)


Fixed-term: The funds for this post are available until 31 August 2020 in the first instance.


A postdoctoral position is available in the group of Professor David Klenerman in the Department of Chemistry at Cambridge University. The project is to develop and optimise the super-resolution imaging of individual protein aggregates in cells, cell lysate and cerebral spinal fluid to map the number, composition, structure and size of the aggregates. Imaging will be performed using a series of designed antibodies that are specific to aggregates and labelled with DNA and using the binding and rebinding of a complementary DNA strand for imaging (DNA paint). This will form part of an ongoing larger project to identify and characterise the protein aggregates that cause Alzheimer's and Parkinson's disease.


Applicants should have a PhD (or equivalent) in single molecule fluorescence or super-resolution microscopy, with experience of instrument building and measurement automation and have an interest in performing multi-disciplinary research. This is an ideal opportunity for physically trained scientist to apply imaging methods to tackle a major biomedical problem.


The position is available immediately.


To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.


Please ensure that you upload your Curriculum Vitae (CV), a covering letter and publications list in the upload section of the online application. If you upload any additional documents that have not been requested, we will not be able to consider these as part of your application. 


Informal inquires can be addressed via email to Professor David Klenerman (


Please quote reference MA15569 on your application and in any correspondence about this vacancy.


The Department holds an Athena SWAN silver award for women in Science, Technology, Engineering, Mathematics, and Medicine.


The University values diversity and is committed to equality of opportunity.


The University has a responsibility to ensure that all employees are eligible to live and work in the UK.


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