Assistant Project Scientist in Biophysics
University of California Berkeley
United States

Assistant Project Scientist in Biophysics 

Job #JPF02614
  • VC Res Other Research Units - QB3 Institute

Recruitment Period

Open date: May 25th, 2020

Next review date: Wednesday, Jun 10, 2020 at 11:59pm (Pacific Time)

Apply by this date to ensure full consideration by the committee.

Final date: Wednesday, Jun 24, 2020 at 11:59pm (Pacific Time)

Applications will continue to be accepted until this date, but those received after the review date will only be considered if the position has not yet been filled.


The Fletcher Laboratory at the University of California, Berkeley is seeking an experimental biophysicist to join its ranks. The overarching goal of the Fletcher Lab is to build a bottom up understanding of the biophysics of living systems. The candidate will develop new tools to investigate how the organization of the actin cytoskeleton impacts the mechanical properties of cells and tissues, and how mutations to cytoskeletal regulatory proteins result in diseases of increased tissue fragility. This project will combine in vitro characterization of the biochemical activity of actin regulatory proteins with cellular and tissue level mechanical measurements.


• Perform experimental biophysics research investigating how the activity of cytoskeletal regulatory proteins impact cell and tissue mechanical properties using Atomic Force Microscopy
• Compare cellular level mechanical measurements with those of reconstituted cytoskeletal networks in vitro
• Maintenance of mammalian cell lines and purification of cytoskeletal proteins
• Maintenance and development of various types of microscopy equipment
• The candidate will contribute to the day to day running of the experimental lab and assist with grant writing and preparation of proposals
• Perform experiments, analyze data and write manuscripts

Basic Qualifications required at the time of application:

• PhD or equivalent international degree

Additional Qualifications must be met by the start of the job:

• A minimum of 4 years of post-doctoral experience

Preferred Qualifications:

• Record of research and publications
• PhD in physics, biophysics, engineering or related subject
• Experience with mammalian cell and tissue culture
• Experience in a broad range of microscopy techniques including Atomic Force Microscopy to measure the mechanical properties of cells and tissues, Spinning Disk Confocal and TIRF Microscopy to image cytoskeletal networks
• Experience with techniques from molecular biology and biochemistry

This position reports to Dr. Daniel Fletcher. The anticipated start date is August 1, 2020. This position is full-time (100%). The initial appointment will be for one year. Thereafter, extension of the appointment is subject to the Academic Researcher (RA) bargaining agreement and extensions will be according to the rank and step, performance and availability of funds. Depending on the size of the applicant pool and funding availability, the lab may hire a second position.

You can refer to the current contract between the University of California and the Academic Researchers at

This position will be open until filled. Please address inquiries to Maria Ruiz

Salary: This is a full-time position. Salary is commensurate with experience.

How to apply:

To apply, please go to the following link:

Letters of reference are not required at this time. We will seek your permission before contacting your references. All letters will be treated as confidential per University of California policy and California state law. Please refer potential referees, including when letters are provided via a third party (i.e., dossier service or career center), to the UC Berkeley statement of confidentiality: prior to submitting their letters.

The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status. For the complete University of California nondiscrimination and affirmative action policy see:


Document requirements
  • Curriculum Vitae - Your most recently updated C.V.
  • Cover Letter - Including a description of research experience.
Reference requirements
  • 3-5 required (contact information only)

If you apply for this position please say you saw it on Physicaloxy


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