Chair Professor of Medicinal Chemistry / Neurochemistry
Radboud University Faculty of Science

Full Professor (Chair) of Medicinal Chemistry / Neurochemistry

  • 32 - 40 hours per week
  • Maximum gross monthly salary: € 8,371
  • Faculty of Science
  • Required background: PhD
  • Duration of the contract: Indefinite period
  • Application deadline: 15 November 2020

We are looking for

You will be responsible for leading an independent research group, which includes establishing and maintaining an internationally competitive research programme that fits on with IMM's research, acquisition of research funding, possibly in collaboration with external academic and/or industrial partners, and supervision and guidance of PhD candidates and scientific staff. Your teaching activities will be part of the Education Institute for Molecular Sciences (which is responsible for the Bachelor's degree programmes in Chemistry, Molecular Life Sciences and Science, and the Master's degree programme in Molecular Sciences) with a focus on teaching in Materials Science and/or Inorganic Chemistry.

We ask

We wish to combine our scientific excellence in organic chemistry and chemical biology with the world-class research in neuroscience at DCN. This combination provides an outstanding opportunity to set-up a new research effort in medicinal chemistry/neurochemistry. The range of possible research areas is broad, but should be strongly driven by a molecular chemistry approach to solving longstanding molecular challenges in neuroscience. Examples of possible research lines include the exploration of (small) molecules modulating targets in neurons, synapses and neural networks, and the use of chemical biology approaches to study key aspects of neurodegenerative diseases such as protein aggregation or the search for biomarkers. A strong datascience component may be included, given the complexity and amount of data likely to be encountered.

The ideal candidate for this position is a medicinal chemist/neurochemist who has a PhD degree in chemistry or biochemistry and uses chemical biology and/or medicinal chemistry approaches to study and modulate molecular mechanisms underlying neurological or neurodegenerative diseases.

We are therefore looking for:
  • An enthusiastic and entrepreneurial scientist with an excellent track record and the potential to conduct research in the field of medicinal chemistry/neurochemistry and initiate a novel, internationally recognised research area within IMM.
  • A researcher who is willing to participate in projects of a multidisciplinary nature and who is willing to collaborate and represent our institute in national and international research organisations.
  • An inspirational lecturer with proven teaching skills and experience with modern ways of conveying knowledge.
  • An academic with proven managerial and organisational experience who will contribute to the administrative and organisational tasks of the Faculty of Science, the IMM research institute and the study programmes they offer.

We are

The Faculty of Science is a complete, student-oriented science faculty where research and education are closely intertwined. The faculty aims to form an academic community with an international character, where staff members from different backgrounds can combine their talents with the common goal of belonging to the leading science faculties in Europe.

You will be appointed as a Full Professor at the Institute for Molecules and Materials (IMM). IMM is a research institute in chemistry and physics, which fosters interdisciplinary research. Its mission is to design and create functional molecules and materials to fundamentally understand their behaviour. IMM comprises 19 research groups active in areas ranging from condensed matter science to organic chemistry and chemical biology. We focus on fundamental research with an open eye for societal applications and educate the next generation of leaders in science and innovation. IMM distinguishes itself from similar institutes by intensive collaborations and interactions between chemists and physicists and between experimentalists and theorists. IMM has a strong infrastructure including large user facilities such as the High Field Magnet Laboratory (HFML), the Free Electron Laser facility FELIX and part of the uNMR-NL facilities.

Chemical biology is a broad research area applying chemical techniques, such as synthetic organic chemistry and analytical methods, to study and modulate biological systems. Chemical biology at IMM benefits from the many close connections between (organic) chemistry groups and research teams at the Radboud Institute for Molecular Life Sciences (RIMLS), the Radboud university medical center (Radboudumc), and the Donders Institute for Neuroscience (DCN). This allows us to cover challenging research projects in a unique way, from molecule to man to patient population. We seamlessly integrate organic synthesis of complex biologically relevant molecules with new omics technologies (including proteomics, metabolomics and RNA-seq), and we use both in vitro and in vivo biochemical approaches to study the role of target molecules in their physiological, intracellular environment. Highlights include unravelling the role and mode of action of sialic acids, novel methods for targeting intracellular proteins, screening new drug targets and subsequent hit-to-lead optimisation and the development of bio-orthogonal click reactions. Current research topics include new methods for single-cell analysis, the discovery of underlying mechanisms of motor neurodegenerative disorders, and the identification of molecules that play a role in the development of the brain. There is also a clear potential for new developments in (chemical) datascience, where we profit from the strong interaction with computational neuroscience at DCN and the state-of-the-art Radboudumc technology centres in bioinformatics, microscopy and mass spectrometry in RIMLS.

Radboud University

We want to get the best out of science, others and ourselves. Why? Because this is what the world around us desperately needs. Leading research and education make an indispensable contribution to a healthy, free world with equal opportunities for all. This is what unites the more than 22,000 students and 5,000 employees at Radboud University. And this requires even more talent, collaboration and lifelong learning. You have a part to play!

We offer

  • Employment: 32 - 40 hours per week.
  • A maximum gross monthly salary of € 8,371 based on a 38-hour working week (salary scale H2).
  • The exact salary depends on the candidate's qualifications and amount of relevant professional experience.
  • In addition to the salary: an 8% holiday allowance and an 8.3% end-of-year bonus.
  • Duration of the contract: indefinite period.
  • You will be able to use our Dual Career and Family Care Services. Our Dual Career and Family Care Officer can assist you with family-related support, help your partner or spouse prepare for the local labour market, provide customized support in their search for employment  and help your family settle in Nijmegen.
  • Have a look at our excellent employment conditions. They include a good work-life balance (among other things because of the excellent leave arrangements), opportunities for development and a great pension scheme.
Radboud University is an equal opportunity employer, committed to building a culturally diverse intellectual community and as such particularly encourages applications from women and minorities

Would you like more information?

For more information about this vacancy, please contact:
Prof.dr. Wilhelm Huck, Full Professor

Apply directly

Please address your application to Prof.dr. Wilhelm Huck and submit it, using the application button, no later than 15 November 2020, 23:59 Amsterdam Time Zone.   

Your application should include the following attachments:

  • Cover letter.
  • A curriculum vitae including a list of publications and the names and contact information (including e-mail addresses) of three potential references.
  • A selection of 3-5 of your most significant publications with brief descriptions of each (please do not attach the original manuscript).
  • A research statement, including a description of how your research programme will add novel aspects to, and align with, IMM's research programme.
  • A teaching statement (maximum 1.5 pages).
The round of interviews is expected to commence during January 2021.

We drafted this vacancy to find and hire our new colleague ourselves. Recruitment agencies are kindly requested to refrain from responding.

If you apply for this position please say you saw it on Physicaloxy


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