PhD Student in Biochemistry of Neurodegeneration
Luxembourg Institute of Health

IBBL (Integrated BioBank of Luxembourg), an autonomous institute organised within the Luxembourg Institute of Health (LIH), is a not-for-profit institute dedicated to supporting biomedical research for the benefit of patients. We provide biospecimen-related services and biobanking infrastructure for applied medical research. We are working with the main Luxembourgish actors in translational medicine and with international academic and industry actors.

IBBL’s culture is based on excellence, trust and innovation. Our team is driven by passion and quality

The University of Luxembourg is a multilingual, international research University. Luxembourg is a dynamic, multicultural country in the heart of Europe with a strong research and development base supported by important organisational resources. The Luxembourg Centre for Systems Biomedicine (LCSB) at the University of Luxembourg offers state-of-the-art facilities and an excellent training environment for early-stage researchers, in particular in the biomedical sciences.

*PhD student in Biochemistry of Neurodegeneration*

*3-year fixed-term contract (renewable), full-time, entry date: December 1st, 2019*

The Enzymology & Metabolism Research Group (LCSB) and IBBL are looking to hire a PhD student as part of the PARK-QC DTU, an interdisciplinary doctoral training unit focusing on ‘Molecular, Organellar and Cellular Quality Control in Parkinson's disease and Other Neurodegenerative Diseases’ and involving several Luxembourgish biomedical research units.

In the collaborative project entitled ‘Search for novel PD biomarkers originating from increased molecular damage and/or deficient molecular quality control systems’, the successful PhD candidate will (establish and) analyse cellular and whole organism models of Parkinson’s disease, as well as PD patient-derived material (e.g. plasma, urine, CSF), applying Crispr/Cas9 technology, imaging-based phenotypic approaches and metabolomics techniques.

Main objectives are to find small molecule disease biomarkers and test small molecule-based therapeutic treatments on the cellular/whole organism models.

*Key Skills, Experience and Qualifications*

• Master degree in Biochemistry, Molecular/Cell Biology, Biotechnology, or a related discipline.
• Strong background in metabolic biochemistry and molecular/cellular biology, as well as good notions in bioinformatics.
• Previous experience with handling model organisms, mammalian cell culture, mass spectrometry and imaging techniques will be considered as important asset(s).
• Excellent English writing and speaking skills are essential

*We offer*

• Project funding available for up to 48 months
• Competitive remuneration; contract subject to public national security system benefits
• A dynamic, exciting and equal opportunity international research environment

*For further information, please contact:*
Dr. Carole Linster :

Located in Luxembourg, LIH offers the opportunity to work in a dynamic, international and multilingual environment that values personal respect and professional achievement based on the highest intellectual and ethical standards. The remuneration for this position shall be based on qualification and experience.

Applications in English including a cover letter, a curriculum vitae including publications, a copy of relevant diplomas and the contact details of 3 referees should be sent before 1st November 2019 through our website Ref.: VD/PHDBN0819/CLFB/IBBL-LCSB

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