Post Doc in Chemical Optimization of Anti-Infective Drug Molecules
Technical University of Munich
Germany

Scientist (PostDoc, m/w/d) in Chemical Optimization of Anti-Infective Drug Molecules

Scientist (PostDoc, m/w/d) - Chemical optimization of anti-infective drug molecules - Vision, Trail blazing, Self-directedness, Excellence --- Is that you? Perfect! We offer the challenge you are seeking! Our profile: Our team mission is to meet the increasing threat of antibiotic resistance by developing innovative treatment options. Within BMBF funded projects, we seek to optimize a novel carbapenemase inhibitor class restoring the activity of the most widely used class of antibiotics (β-Lactams) in collaboration with the Helmholtz Institutes in Neuherberg (structure analysis via NMR and X-ray) and Braunschweig (medicinal chemistry). In addition, our inhibitor class combines beta-lactamase inhibition with standalone antibiotic activity in a unique manner. The focus of this project is the optimization and activity profiling of fragment-based inhibitors.

Your profile:

- PhD degree in Chemistry, Biochemistry, Molecular Biotechnology with outstanding result
- Experience in biochemical assay development, optimization and validation
- Experience in target- and fragment-based compound optimization
- MedChem experience in industry setting is a plus
- Enthusiasm for translational science and entrepreneur personality
- Excellent team spirit, presentation, and communication skills

Your tasks:

- Activity testing of inhibitory compounds in biochemical assays
- Contribution to fragment based compound design and optimization
- Supervision of external compound synthesis
- SAR analysis and management of compound database
- Supervision of technical staff

We offer:

- Ambitious and innovation oriented team committed to antibacterial drug development
- Close collaboration with in house diagnostic / medical microbiology department, HMGU, HZI, and industry consultants
- Well-equipped laboratory in our institute close to Munich city center
- Full time position as scientist / PostDoc (m/w/d), currently secured for 18 months (salary according to TV-L)
- Perspective to be part of a spin-off endeavor

Application:

Are you excited to secure for infectious disease treatment?
Great! We are looking forward to your email application until June 15th:

Dr. Hannelore Meyer / +89 15203112080 / Hannelore.Meyer@tum.de / http://www.mikrobio.med.tu-muenchen.de/

Further questions? We are happy to receive your email or phone call!
TUM seeks to increase the portion of female employees. Qualified females are, therefore, explicitly encouraged to apply. Severely disabled persons with essentially comparable qualifications will be preferentially hired.

Hinweis zum Datenschutz:

Im Rahmen Ihrer Bewerbung um eine Stelle an der Technischen Universität München (TUM) übermitteln Sie personenbezogene Daten. Beachten Sie bitte hierzu unsere Datenschutzhinweise gemäß Art. 13 Datenschutz-Grundverordnung (DSGVO) zur Erhebung und Verarbeitung von personenbezogenen Daten im Rahmen Ihrer Bewerbung. Durch die Übermittlung Ihrer Bewerbung bestätigen Sie, dass Sie die Datenschutzhinweise der TUM zur Kenntnis genommen haben.

Kontakt: Dr. Hannelore Meyer / +89 15203112080 / Hannelore.Meyer@tum.de / http://www.mikrobio.med.tu-muenchen.de/


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